string path = "test.txt"; FileStream fs = new FileStream(path, FileMode.Open); StreamReader sr = new StreamReader(fs); char[] separator = new char[] { ' ', ',', ' ', ' ', ' ' }; string txt = sr.ReadToEnd().Trim().Replace(" ", " "); string[] lines = txt.Split(separator); List<float> result = new List<float>(1024); string[] nums; float tmp; for (int i = 0; i < lines.Length; i++) { nums = lines[i].Trim().Split(separator); foreach(var num in nums) { if (num == "") continue; if(float.TryParse(num, out tmp)) { result.Add(tmp); } else { Debug.Log("Format error at line " + (i + 1)+ ": " + num); } } } sr.Close(); fs.Close();