DELIVERING HIGHLY ACCURATE LONG READS TO DRIVE DISCOVERY IN LIFE SCIENCE
Single Molecule, Real-Time (SMRT) Sequencing is the core technology powering our long-read sequencing platforms. This innovative approach was the first of its kind and is now a proven technology used in all fields of life science.
Learn how to go from DNA to discovery with SMRT Sequencing in this short video.
Original Publication: Eid, J., et al. (2009) Real-time DNA sequencing from single polymerase molecules. Science, 323(5910), 133–138.
| Long Reads
With reads tens of kilobases in length you can readily assemble complete genomes and sequence full-length transcripts. |
| High Accuracy
Sequencing free of systematic error achieves >99.999% consensus accuracy. |
| Uniform Coverage
No bias based on GC content means you can sequence through region inaccessible to other technologies. |
| Single-Molecule Resolution
Capturing sequence data from native DNA or RNA molecules enables highly accurate long reads with >99% single-molecule accuracy. |
| Epigenetics
With no PCR amplification step, base modifications are directly detected during sequencing. |
Explore the full range of SMRT Sequencing applications.
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Whole Genome Sequencing
For humans, plants, animals and microbes including de novo assembly and variant detection |
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Complex Populations
Understand variants among bacterial, viral and cancer cell populations |
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RNA Sequencing
In-depth analysis of cDNA sequences across the entire transcriptome or targeted genes |
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Epigenetics
Detect DNA modifications in your samples while you sequence on the PacBio platform |
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Targeted Sequencing
Study relevant genome targets across any regions of interest |