[System.Runtime.InteropServices.DllImport("user32.dll")] //申明API函数 public static extern bool RegisterHotKey( IntPtr hWnd, // handle to window int id, // hot key identifier uint fsModifiers, // key-modifier options Keys vk // virtual-key code ); [System.Runtime.InteropServices.DllImport("user32.dll")] //申明API函数 public static extern bool UnregisterHotKey( IntPtr hWnd, // handle to window int id // hot key identifier ); protected override void WndProc(ref Message m) { const int WM_HOTKEY = 0x0312; if (WM_HOTKEY == m.Msg) { if (m.WParam.ToInt32() == 101) { hidWindows(); } } base.WndProc(ref m); } //显示 or 隐藏 private void hidWindows() { if (this.Visible == false) { this.Visible = true; this.TopMost = true; } else { this.Visible = false; } } 注册快捷键: /* None = 0, Alt = 1, Ctrl = 2, Shift = 4, WindowsKey = 8 */ RegisterHotKey(Handle, 101, 2, Keys.Q);