How are you与How are you doing,有何不同呢?
貌似没有不同……
中国教科书式的回答是"Fine, thank you, and you?"
随便一点"Great/Wonderful/Well/Good/Not bad"
有区别的是How do you do?
这个的回答一般比较固定就是同样来一句How do you do?
ref:
http://english.stackexchange.com/questions/73766/difference-between-how-are-you-and-how-are-you-doing