I am 54 and started in the profession in 1981. Advice? Always always always keep your skills up to date.
Never get comfortable with the 'I am set, I got it all, I made it, I can now walk into any job with what I have' attitude. That would be the kiss of death.
I don't care who you are, where you have worked, what you did, what school you did or didn't go to, if you don't constantly keep improving your skills, constantly dive into new technologies, stay on the upward curve of what skill sets are being asked for in the profession, you will fail eventually.
This is a world of 'what have you done for me lately' and 'tell me why I need you'. Doesn't matter if you are 22 or 52, you need to provide value, period.