今天把开发环境一直到Windows7下，在IIS7.5中部署站点的时候遇到了这个问题，现在把我的解决方案贴出来。
错误信息：
Server Error in Application "DEMOSITE"
Internet Information Services 7.5Error Summary
HTTP Error 500.23 - Internal Server Error
An ASP.NET setting has been detected that does not apply in Integrated managed pipeline mode.
Detailed Error Information
Module ConfigurationValidationModule
Notification BeginRequest
Handler PageHandlerFactory-Integrated
Error Code 0x80070032Requested URL http://localhost:80/Default.aspx
Physical Path F:\Projects\*\Default.aspx
Logon Method Not yet determined
Logon User Not yet determined
Most likely causes:
This application defines configuration in the system.web/httpHandlers section.
Things you can try:
Migrate the configuration to the system.webServer/handlers section. You can do so manually or by using AppCmd from the command line - for example, %SystemRoot%\system32\inetsrv\appcmd migrate config "Default Web Site/". Using appcmd to migrate your application will enable it to work in Integrated mode, and continue to work in Classic mode and on previous versions of IIS.
If you are certain that it is OK to ignore this error, it can be disabled by setting system.webServer/validation@validateIntegratedModeConfiguration to false.
Alternatively, switch the application to a Classic mode application pool -
for example, appcmd set app "Default Web Site/" /applicationPool:"Classic .NET AppPool". Only do this if you are unable to migrate your application.
(Set "Default Web Site" and "Classic .NET AppPool" to your application path and application pool name)
Links and More InformationIntegrated mode is the preferred mode for running ASP.NET applications on IIS 7.0 and above.
View more information »解决办法：1、打开ISS，进入在右侧列表中找到“高级设置” Advanced Setting 打开，找到 “应用程序池”Application Pool 一栏。
接下来介绍两种解决办法:
方法一、将Application pool 设置为 "Classic .Net AppPool" 即可；
方法二、找到对应的 应用程序池（Application pool ）的名字，我这里是 demosite在IIS主页，找到 "Application Pools"在中间列表中打开 "demosite",将 Managed pipeline mode 由 Integrated 改为 Classic 即可，如下图问题解决！
