var headers = app.Context.Request.Headers; Type hdr = headers.GetType(); PropertyInfo ro = hdr.GetProperty("IsReadOnly", BindingFlags.Instance | BindingFlags.NonPublic | BindingFlags.IgnoreCase | BindingFlags.FlattenHierarchy); // Remove the ReadOnly property ro.SetValue(headers, false, null); // Invoke the protected InvalidateCachedArrays method hdr.InvokeMember("InvalidateCachedArrays", BindingFlags.InvokeMethod | BindingFlags.NonPublic | BindingFlags.Instance, null, headers, null); // Now invoke the protected "BaseAdd" method of the base class to add the // headers you need. The header content needs to be an ArrayList or the // the web application will choke on it. hdr.InvokeMember("BaseAdd", BindingFlags.InvokeMethod | BindingFlags.NonPublic | BindingFlags.Instance, null, headers, new object[] { "CustomHeaderKey", new ArrayList {"CustomHeaderContent"}} ); // repeat BaseAdd invocation for any other headers to be added // Then set the collection back to ReadOnly ro.SetValue(headers, true, null);