static class Program { [DllImport("Toolhelp.dll")] public static extern IntPtr CreateToolhelp32Snapshot(uint flags, uint processid); [DllImport("Toolhelp.dll")] public static extern int Process32First(IntPtr handle, ref PROCESSENTRY32 pe); [DllImport("Toolhelp.dll")] public static extern int Process32Next(IntPtr handle, ref PROCESSENTRY32 pe); /// <summary> /// 应用程序的主入口点。 /// </summary> [MTAThread] static void Main() { IntPtr handle = CreateToolhelp32Snapshot((uint)SnapShotFlags.TH32CS_SNAPPROCESS, 0); int count = 0; if ((int)handle != -1) { PROCESSENTRY32 pe32 = new PROCESSENTRY32(); pe32.dwSize = (uint)Marshal.SizeOf(typeof(PROCESSENTRY32)); int bMore = Process32First(handle, ref pe32); while (bMore == 1) { if (pe32.szExeFile == "WareHouse.exe")//需要与程序保持一致 count++; bMore = Process32Next(handle, ref pe32); } } if (count > 1) { MessageBox.Show("程序已经运行!"); return; } else Application.Run(MainFram.GetInstance()); } [StructLayout(LayoutKind.Sequential)] public struct PROCESSENTRY32 { public uint dwSize; public uint cntUsage; public uint th32ProcessID; public IntPtr th32DefaultHeapID; public uint th32ModuleID; public uint cntThreads; public uint th32ParentProcessID; public int pcPriClassBase; public uint dwFlags; [MarshalAs(UnmanagedType.ByValTStr, SizeConst = 260)]//注意,此处为宽字符 public string szExeFile; public uint th32MemoryBase; public uint th32AccessKey; } public enum SnapShotFlags : uint { TH32CS_SNAPHEAPLIST = 0x00000001, TH32CS_SNAPPROCESS = 0x00000002, TH32CS_SNAPTHREAD = 0x00000004, TH32CS_SNAPMODULE = 0x00000008, TH32CS_SNAPALL = (TH32CS_SNAPHEAPLIST | TH32CS_SNAPPROCESS | TH32CS_SNAPTHREAD | TH32CS_SNAPMODULE), TH32CS_GETALLMODS = 0x80000000 } }