效果图：
添加扩展类
public static class DataGridExtend { /// <summary> /// 获取DataGrid控件单元格 /// </summary> /// <param name="dataGrid">DataGrid控件</param> /// <param name="rowIndex">单元格所在的行号</param> /// <param name="columnIndex">单元格所在的列号</param> /// <returns>指定的单元格</returns> public static DataGridCell GetCell(this DataGrid dataGrid, int rowIndex, int columnIndex) { DataGridRow rowContainer = dataGrid.GetRow(rowIndex); if (rowContainer != null) { DataGridCellsPresenter presenter = GetVisualChild<DataGridCellsPresenter>(rowContainer); DataGridCell cell = (DataGridCell)presenter.ItemContainerGenerator.ContainerFromIndex(columnIndex); if (cell == null) { dataGrid.ScrollIntoView(rowContainer, dataGrid.Columns[columnIndex]); cell = (DataGridCell)presenter.ItemContainerGenerator.ContainerFromIndex(columnIndex); } return cell; } return null; } /// <summary> /// 获取DataGrid的行 /// </summary> /// <param name="dataGrid">DataGrid控件</param> /// <param name="rowIndex">DataGrid行号</param> /// <returns>指定的行号</returns> public static DataGridRow GetRow(this DataGrid dataGrid, int rowIndex) { DataGridRow rowContainer = (DataGridRow)dataGrid.ItemContainerGenerator.ContainerFromIndex(rowIndex); if (rowContainer == null) { dataGrid.UpdateLayout(); dataGrid.ScrollIntoView(dataGrid.Items[rowIndex]); rowContainer = (DataGridRow)dataGrid.ItemContainerGenerator.ContainerFromIndex(rowIndex); } return rowContainer; } /// <summary> /// 获取父可视对象中第一个指定类型的子可视对象 /// </summary> /// <typeparam name="T">可视对象类型</typeparam> /// <param name="parent">父可视对象</param> /// <returns>第一个指定类型的子可视对象</returns> public static T GetVisualChild<T>(Visual parent) where T : Visual { T child = default(T); int numVisuals = VisualTreeHelper.GetChildrenCount(parent); for (int i = 0; i < numVisuals; i++) { Visual v = (Visual)VisualTreeHelper.GetChild(parent, i); child = v as T; if (child == null) { child = GetVisualChild<T>(v); } if (child != null) { break; } } return child; } }
用法：
var cell = grid.GetCell(2,3); if (cell != null) { cell.IsEnabled = false; cell.Background = Brushes.LightGray; }
以上是设置datagrid第三行第四列单元格的背景色和Enable属性。