http://livedocs.adobe.com/flex/gumbo/html/WSB9897D78-31A2-4565-8F14-969585DC7A20.html
Adobe® Flex® data access components use remote procedure calls to interact with server environments, such as PHP, Adobe ColdFusion, and Microsoft ASP.NET. The remote procedure calls provide data to applications built with Flex and send data to back-end data sources. For an introduction to data access components, see Using data-driven UI components.