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J Rheumatol. 2011 Feb 15. [Epub ahead of print] Repair of Radiographic Joint Damage Following Treatment with Etanercept in Psoriatic Arthritis Is Demonstrable by 3 Radiographic Methods.Eder L, Chandran V, Gladman DD. From the Psoriatic Arthritis Program, Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Western Hospital, Toronto, Ontario, Canada. AbstractOBJECTIVE: Psoriatic arthritis (PsA) is characterized by varied radiographic features. We describe a patient with PsA with severe radiographic damage that improved significantly following treatment with etanercept. The improvement was documented by several methods of radiographic assessment. METHODS: Etanercept was introduced in September 2005. Radiographs of the hands and feet were read using 3 methods: the modified Steinbrocker method, the van der Heijde (vdH) modification of the Sharp method, and the Ratingen scoring system. RESULTS: In July 2009, radiographs of the hands and feet showed improvement in erosion score and joint space narrowing, while bony proliferation remained the same [43 by modified Steinbrocker, 26 by the vdH Sharp score (12 for erosions and 14 for joint space narrowing), and 56 by the Ratingen (18 for erosion and 38 for proliferation]. CONCLUSION: The 3 radiographic methods were useful in demonstrating improvement in joint scores. The modified Steinbrocker method, which is the simplest, was able to reveal improvement in our patient.
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三种影像学方法证实依那西普治疗银屑病关节炎有关节修复作用 Eder L, Chandran V, et al,J Rheumatol. 2011 Feb 15. [Epub ahead of print] 目的:银屑病关节炎(PsA) 影像学特征多种多样。我们报告一例有严重影像学破坏的PsA患者经过依那西普治疗后得到显著改善。这种改善经过多种影像学评估方法得以证实。 方法: 2005年9月患者开始应用依那西普。影像学的手足片通过3种方法阅读:改良的Steinbrocker法,Sharp评分中改良的 van der Heijde (vdH)法和Ratingen评分系统。 结果: 2009年7月, 手和足的影像学评估显示侵蚀积分和关节间隙狭窄有所改善,而骨质增生无变化[改良的Steinbrocker法为43，vdH积分为26 (侵蚀评分12，关节间隙狭窄评分14), Ratingen评分系统为56 (侵蚀评分18，增生评分38]。 结论:3种影像学方法都有助于证实关节积分的改善。改良后的Steinbrocker方法最简单，并能显示病人的改善情况。 |